Principales publications

Glondu-Lassis M, Dromard M, Lacroix-Triki M, Nirdé P, Puech C, Knani D, Chalbos D, Freiss G. PTPL1/PTPN13 Regulates Breast Cancer Cell Aggressiveness through Direct Inactivation of Src Kinase. Cancer Res. 2010 May 25. [Epub ahead of print]PMID: 20501847

Nirdé P, Derocq D, Maynadier M, Chambon M, Gary-Bobo M, Garcia M (2010) Heat shock cognate 70 protein secretion as a new growth arrest signal for cancer cells, Oncogene, 29:117-27.

Wang X, Belguise K, O’Neill C, Eddy SF, Mineva ND, Yu Z, Sánchez-Morgan N, Min C, Trinkaus-Randall V, Chalbos D, Sonenshein GE (2009) RelB NF-B Represses Oestrogen Receptor Expression via Induction of the Zinc Finger Protein Blimp1. Mol Cell Biol, 29:3832-3844.

Revillion F, Puech C, Rabenoelina F, Chalbos D, Peyrat JP, Freiss G. Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer. Int J Cancer 2008; 124: 638-643.

Ndlovu MN, Van Lint C, Van Wesemael K, Callebert P, Chalbos D, Haegeman G, Vanden Berghe W (2009) Hyperactivated NFB and AP1 transcription factors promote highly accessible chromatin and constitutive transcription across the IL6 gene promoter in metastatic breast cancer cells Mol Cell Biol, 29:3832-44.

Glondu-Lassis M, Dromard M, Chavey C, Puech C, Fajas L, Hendriks W, Freiss G. Downregulation of protein tyrosine phosphatase PTP-BL represses adipogenesis. Int J Biochem Cell Biol 2009; 41: 2173-2180.

Brevet D, Gary-Bobo M, Raehm L, Richeter S, Hocine O, Amro K, Loock B, Couleaud P, Frochot C, Morere A, Maillard P, Garcia M, Durand JO. Mannose-targeted mesoporous silica nanoparticles for photodynamic therapy. Chem Commun (Camb) 2009: 1475-1477.

Maynadier, M., Ramirez, J-M., Cathiard, A-M., Platet, N., Gras, D., Gleizes, M., Sheikh, S., Nirdé, P., and Garcia, M. Unliganded estrogen receptor alpha inhibits breast cancer cell growth through interaction with cyclin-dependent kinase inhibitor (p21WAF1). Faseb J 2008; 22: 671-681

Jeanjean A, Gary-Bobo M, Nirde P, Leiris S, Garcia M, Morere A. Synthesis of new sulfonate and phosphonate derivatives for cation-independent mannose 6-phosphate receptor targeting. Bioorg Med Chem Lett 2008; 18: 6240-6243

Dromard M, Bompard G, Glondu-Lassis M, Puech C, Chalbos D, Freiss G. The putative tumour suppressor gene PTPN13/PTPL1 induces apoptosis through IRS-1 dephosphorylation Cancer Res, 67: 6806-6813, 2007.

Wang, X., Belguise, K., Kersual, N., Kirsch, K. H., Mineva, N. D., Galtier, F., Chalbos, D., and Sonenshein, G. E. Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2. Nat Cell Biol, 9: 470-478, 2007.

Basbous, J., Chalbos, D., Hipskind, R., Jariel-Encontre, I., and Piechaczyk, M. Ubiquitylation-independent proteasomal degradation of Fra-1 is antagonized by Erk 1/2 pathway-mediated phosphorylation of a unique C-terminal destabilizer. Mol Cell Biol, 2007, 27 : 3936-50

Esslimani M, Thezenas S, Simony-Lafontaine J, Kramar A, Lavaill R, Chalbos D, Rochefort H (2007). Expression of Fatty Acid Synthase and Progesterone receptor are increased independently in early steps of mammary carcinogenesis Int J Cancer, 120:224-249.

Freiss G, Galtier F, Puech C, Aknin C, Maudelonde T, Chalbos D, Vignon F (2005) Anti-growth factor activities of benzothiphenes in human breast cancer cells. J Steroid Biochem and Molecular Biology, 94, 451-460.

Bompard G, Sharp SJ, Freiss G, Machesky LM (2005). Involvement of Rac in actin cytoskeleton induced by MIM-B. J Cell Science, 118, 5393-5403.

Belguise K, Kersual N, Galtier F, Chalbos D. Fra-1 expression level regulates proliferation and invasiveness of breast cancer cells. Oncogene, 24, 1434-1444, 2005..