Liste des publications

Jacot W, Theillet C, Guiu S, Lamy PJ. Targeting triple-negative breast cancer and high-grade ovarian carcinoma: refining BRCAness beyond BRCA1/2 mutations? Future Oncol. 2015;11(4):557-9. doi: 10.2217/fon.14.268. No abstract available.


Colombo PE, du Manoir S, Orsett B, Bras-Gonçalves R, Lambros MB, MacKay A, Nguyen TT, Boissière F, Pourquier D, Bibeau F, Reis-Filho JS, Theillet C. Ovarian carcinoma patient derived xenografts reproduce their tumor of origin and preserve an oligoclonal structure. Oncotarget. 2015 Sep 29;6(29): 28327-40. doi: 10.18632/oncotarget. 5069.


Bach AS, Derocq D, Laurent-Matha V, Montcourrier P, Sebti S, Orsetti B, Theillet C, Gongora C, Pattingre S, Ibing E, Roger P, Linares LK, Reinheckel T, Meurice G, Kaiser FJ, Gespach C, Liaudet-Coopman E. Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells. Oncotarget. 2015 Sep 29;6(29) : 28084-103.


Houlès T, Rodier G, Le Cam L, Sardet C, Kirsh O. Description of an optimized ChIP-seq analysis pipeline dedicated to genome wide identification of E4F1 binding sites in primary and transformed MEFs.
Genom Data. 2015 Jul 14;5:368-70.  eCollection 2015 Sep.


Rodier G, Kirsh O, Baraibar M, Houlès T, Lacroix M, Delpech H, Hatchi E, Arnould S, Severac D, Dubois E, Caramel J, Julien E, Friguet B, Le Cam L, Sardet C. The Transcription Factor E4F1 Coordinates CHK1-Dependent Checkpoint and Mitochondrial Functions. Cell Rep. 2015 Apr 14;11(2):220-33. doi: 10.1016/j.celrep.2015.03.024. Epub 2015 Apr 2.


Paul C, Sardet C, Fabbrizio E. The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion. Biol Open. 2015 Feb 13;4(3):312-6. doi: 10.1242/bio. 201411247.


Orsetti B, Selves J, Bascoul-Mollevi C, Lasorsa L, Gordien K, Bibeau F, Massemin B, Paraf F, Soubeyran I, Hostein I, Dapremont V, Guimbaud R, Cazaux C, Longy M, Theillet C. Impact of chromosomal instability on colorectal cancer progression and outcome. BMC Cancer. 2014 Feb 22;14(1):121. [Epub ahead of print]


Du Manoir S, Orsetti B, Bras-Gonçalves R, Nguyen TT, Lasorsa L, Boissière F, Massemin B, Colombo PE, Bibeau , Jacot W, Theillet C. Breast tumor PDXs are genetically plastic and correspond to a subset of aggressive cancers prone to relapse. Mol Oncol. 2013 Dec 19. pii: S1574- 7891 (13)0 0172 -5. doi: 10.1016/j.molonc .2013. 11. 010. [Epub ahead of print]


Colombo PE, Fabbro M, Theillet C, Bibeau F, Rouanet P, Ray-Coquard I. Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer. Crit Rev Oncol Hematol. 2013 Sep 8. pii: S1040-8428 (13)00194-7. doi: 10.1016/j. critrevonc.2013.08.017. [Epub ahead of print]


Rème T, Hose D, Theillet C, Klein B. Modeling risk stratification in human cancer. Bioinformatics. 2013 May 1;29(9):1149-57. doi: 10.1093/bioinformatics/btt124. Epub 2013 Mar 14


Wang J, Pursell NW, Samson ME, Atoyan R, Ma AW, Selmi A, Xu W, Cai X, Voi M, Savagner P, Lai CJ. Potential Advantages of CUDC-101, a Multi-Targeted HDAC, EGFR, and HER2 Inhibitor, in Treating Drug Resistance and Preventing Cancer Cell Migration and Invasion. Mol Cancer Ther. 2013 Jun;12(6):925-36.

Lavigne C, Slater K, Gajanayaka N, Duguay C, Arnau Peyrotte E, Fortier G, Simard M, Kell AJ, Barnes ML, Thierry AR. Influence of lipoplex surface charge on siRNA delivery: application to the in vitro downregulation of CXCR4 HIV-1 co-receptor. Expert Opin Biol Ther. 2013 Jul;13 (7):973-85.

Nassour M, Idoux-Gillet Y, Selmi A, Côme C, Faraldo ML, Deugnier MA, Savagner P. Slug Controls Stem/Progenitor Cell Growth Dynamics during Mammary Gland Morphogenesis. PLoS One. 2012;7(12):e53498. doi: 10.1371 / journal.pone. 0053498. Epub 2012 Dec 27.


Norris V, Loutelier-Bourhis C, Thierry A. How did metabolism and genetic replication get married? Orig Life Evol Biosph. 2012 Oct;42(5):487-95. doi: 10.1007/s11084-012-9312-3. Epub 2012 Oct 14.


Norris V, Thierry A, Amar P, Holland IB, Molina F. The mimic chain reaction. J Mol Microbiol Biotechnol. 2012;22(5):335-43. doi: 10.1159/000345328. Epub 2012 Dec 5.


Guedj M, Marisa L, de Reynies A, Orsetti B, Schiappa R, Bibeau F, Macgrogan G, Lerebours F, Finetti P, Longy M, Bertheau P, Bertrand F, Bonnet F, Martin AL, Feugeas JP, Bièche I, Lehmann-Che J, Lidereau R, Birnbaum D, Bertucci F, de Thé H, Theillet C. A refined molecular taxonomy of breast cancer. Oncogene. 2012 Mar 1;31(9):1196-206

Fabregue M, Bringay S, Poncelet P, Teisseire M, Orsetti B. Mining microarray data to predict the histological grade of a breast cancer. J Biomed Inform. 2011 Dec;44 Suppl 1:S12-6


Le Bechec A, Portales-Casamar E, Vettter G, Moes M, Zindy PJ, Saumet A, Arenillas D, Theillet C, Wasserman WW, Lecellier CH, Friederich E. MIR@NT@N: a framework integrating transcription factors, microRNAs and their targets to identify sub-network motifs in meta-regulation network model. BMC Bioinformatics. 2011 Mar 4;12(1):67.


Charles Theillet. What do we learn from HER2-positive breast cancer genomic profiles? Breast Cancer Research 2010, 12:107


Tuduri S, Crabbe L, Tourrière H, Coquelle A, Pasero P. Does interference between replication and transcription contribute to genomic instability in cancer cells? Cell Cycle. 2010 May 15;9(10):1886-92


Herfs M, Hubert P, Suarez-Carmona M, Reschner A, Saussez S, Berx G, Savagner P, Boniver J, Delvenne P. Regulation of p63 isoforms by snail and slug transcription factors in human squamous cell carcinoma. Am J Pathol. 2010 Apr;176(4):1941-9.


Docquier A, Harmand PO, Fritsch S, Chanrion M, Darbon JM, Cavaillès V. The Transcriptional Coregulator RIP140 Represses E2F1 Activity and Discriminates Breast Cancer Subtypes. Clin Cancer Res. 2010 Jun 1;16(11):2959-70


Tuduri S, Crabbé L, Conti C, Tourrière H, Holtgreve-Grez H, Jauch A, Pantesco V, De Vos J, Thomas A, Theillet C, Pommier Y, Tazi J, Coquelle A, Pasero P. Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol. 2009 Nov;11(11):1315-24


Klymkowsky MW, Savagner P. Epithelial-Mesenchymal Transition. A Cancer Researcher's Conceptual Friend and Foe. Am J Pathol 2009 May;174(5):1588-93.


Arnoux V, Nassour M, L'Helgoualc'h A, Hipskind RA, Savagner P. Erk5 Controls Slug Expression and Keratinocyte Activation during Wound Healing. Mol Biol Cell 2008 Nov; 19: 4738-49


Chanrion, M., Fontaine, H., Rodriguez, C., Negre, V., Bibeau, F., Theillet, C., Henaut, A., and Darbon, J. M. A new molecular breast cancer subclass defined from a large scale real-time quantitative RT-PCR study. BMC Cancer, 7: 39, 2007.


Moll, F., Millet, C., Noel, D., Orsetti, B., Bardin, A., Katsaros, D., Jorgensen, C., Garcia, M., Theillet, C., Pujol, P., and Francois, V. Chordin is underexpressed in ovarian tumors and reduces tumor cell motility. Faseb J, 20: 240-250, 2006.


Olivier, M., Langerod, A., Carrieri, P., Bergh, J., Klaar, S., Eyfjord, J., Theillet, C., Rodriguez, C., Lidereau, R., Bieche, I., Varley, J., Bignon, Y., Uhrhammer, N., Winqvist, R., Jukkola-Vuorinen, A., Niederacher, D., Kato, S., Ishioka, C., Hainaut, P., and Borresen-Dale, A. L. The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer. Clin Cancer Res, 12: 1157-1167, 2006.


Orsetti, B., Nugoli, M., Cervera, N., Lasorsa, L., Chuchana, P., Rouge, C., Ursule, L., Nguyen, C., Bibeau, F., Rodriguez, C., and Theillet, C. Genetic profiling of chromosome 1 in breast cancer: mapping of regions of gains and losses and identification of candidate genes on 1q. Br J Cancer, 95: 1439-1447, 2006.

Come, C., F. Magnino, et al. "Snail and Slug play distinct roles during breast carcinoma progression." Clin Cancer Res, 12 : 5395-5402, 2006.

Bardet, P. L., B. Horard, et al. "The ERRalpha orphan nuclear receptor controls morphogenetic movements during zebrafish gastrulation." Dev Biol 281(1): 102-111, 2005.

Gelsi-Boyer, V., B. Orsetti, et al. "Comprehensive profiling of 8p11-12 amplification in breast cancer." Mol Cancer Res 3(12): 655-667, 2005.


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