Valérie Attuil-Audenis

Ph.D, Responsable département produits, Covalab

“Highly-loaded hydrophilic ADC drug linker platform”

Contact IRCM : Thierry Chardès

22 & 23 june 2020 : 8th Antibody Industrial Symposium « Multispecific Antibodies, Ab-like Molecules and Adoptive Cell Therapy for Fighting Diseases »At Montpellier, Le CorumAs leaders of the organizing committee and members of the scientific committee, IRCM scientists are proud to share with you the next AIS2020 programme. This symposium will present new scientific advances and perspectives on multispecies antibodies, immunocytokines and CAR-T cells. The objectives are to foster interactions between academic researchers, clinicians, physicians and pharmacists, and industrialists in the field of therapeutic antibodies and immunotherapy. Organization : LabEx MAbImprove & MabDesignInstitutional support: University of Montpellier, MUSE, Region OccitanieMore : https://aiscongress.com/  

Postdoctoral Position in Modeling of the Tumor MicroenvironmentDate limite de candidature : 31/12/2019The Colinge Laboratory Cancer Bioinformatics and Systems Biology at IRCM (Cancer Research Institute of Montpellier) is looking for a talented postdoctoral fellow to work on the evolution of the tumor microenvironment (TME) in response to therapy. This computational work will build upon on-going developments conducted in the lab to infer cellular interactions taking place in the TME. Both single-cell and bulk transcriptomics configurations will be considered. A significant part of the research will relate to lung adenocarcinoma and involve a consortium of expert laboratories in lung cancer and mouse models thereof, animal computer tomography, and 3D imaging. The postdoc position is funded for three years; a 1-year contract will be offered first and extended for another two years based on performance. Preferred qualifications are a bioinformatics Ph.D. with solid computational skills or a mathematics, physics, or computer science Ph.D. with strong interests in life science applications. Interested applicants should e-mail their CV, a letter of motivation, and the names and e-mails of 2 references to Prof Jacques Colinge (at inserm.fr). Applications will be studied immediately. Selected publicationsAlame et al., The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities, bioRxiv, 2019Lehmann et al., In Vivo Large-Scale Mapping Of Protein Turnover In The Human Cerebrospinal Fluid, bioRxiv, 2019Blomen et al. Gene essentiality and synthetic lethality in haploid human cells. Science, 2015Pichlmair et al. Viral immune modulators perturb the human molecular network by common and unique strategies, Nature, 2012Stukalov et al. Deconvolution of targeted protein-protein interaction maps. J Proteome Res, 2012  

L’Institut de Recherche en Cancérologie de Montpellier a inauguré, le 18 septembre 2019, une plateforme d’imagerie par cytométrie de masse basée sur la technologie CyTOF/Hyperion permettant, pour la première fois en France, de cartographier le microenvironnement cellulaire et l’hétérogénéité tumorale. Cette technologie, unique en France, est porteuse de nouveaux espoirs pour les patients. Elle devrait permettre, à l’heure où l’immunothérapie a des effets cliniques spectaculaires, y compris chez des patients en échappement thérapeutique, d’approfondir la connaissance sur ces nouvelles thérapies anticancéreuses.    Communiqué de presse Inauguration CyTOF IRCM