Research
Immunity and cancer : N. Bonnefoy

RESEARCH TOPICS

Our laboratory aims to identify and target molecular and cellular immunosuppressive mechanisms that contribute to tumor escape from immune surveillance to improve patient response to treatment and survival.

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MAIN PUBLICATIONS

Glasson Y, Chépeaux L-A, Dumé A-S, Jay P, Pirot N, Bonnefoy N, Michaud H-A A 31-plex panel for high-dimensional single-cell analysis of murine preclinical models of solid tumors by imaging mass cytometry. Front Immunol. 2022;13. doi:10.3389/fimmu.2022.1011617

Faget J, Peters S, Quantin X, Meylan E, Bonnefoy N Neutrophils in the era of immune checkpoint blockade. J Immunother Cancer. 2021;9(7):e002242. doi:10.1136/jitc-2020-002242

Chabab G, Boissière-Michot F, Mollevi C, Ramos J, Lopez-Crapez E, Colombo P-E, Jacot W, Bonnefoy N, Lafont V Diversity of Tumor-Infiltrating, ?? T-Cell Abundance in Solid Cancers. Cells. 2020;9(6). doi:10.3390/cells9061537

Perrot I, Michaud H-A, Giraudon-Paoli M, Augier S, Docquier A, Gros L, Courtois R, Jecko D, Becquart O, Rispaud-Blanc H, Gauthier L, Rossi B, Chanteux S, Gourdin N, Amigues B, Roussel A, Bensussan A, Eliaou J-F, Bastid J, Romagné F, Morel Y, Narni-Mancinelli E, Vivier E, Paturel C, Bonnefoy N Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies. Cell Rep. 2019;27(8):2411-2425.e9. doi:10.1016/j.celrep.2019.04.091

Laprevotte E, Cochaud S, du Manoir S, Lapierre M, Dejou C, Philippe M, Giustiniani J, Frewer K, Sanders A, Jiang W, Michaud H-A, Colombo P-E, Bensussan A, Alberici G, Bastid J, Eliaou J-F, Bonnefoy N The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway. Oncotarget. 2017;8(69):113360-113372. doi:10.18632/oncotarget.23008


Team

Team Leader  : Nathalie Bonnefoy
 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle
34298 Montpellier cedex 5

Tél. : 33 (0)4 67 61 24 40
Fax : 33 (0)4 67 61 37 87
nathalie.bonnefoy@inserm.fr

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© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés