Research
Tumor microenvironnement and resistance to treatment : A. Turtoi

activities

Our lab is interested in understanding and targeting the communication between cancer and stromal cells to offer new therapeutic insights.

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main Publications

Neiveyans M, Melhem R, Arnoult C, Bourquard T, Jarlier M, Busson M, Laroche A, Cerutti M, Pugnière M, Ternant D, Gaborit N, Chardès T, Poupon A, Gouilleux-Gruart V, Poul M-A A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions. MAbs. 2019;11(3):593-605. doi:10.1080/19420862.2018.1564510

Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios A, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases. Oncogene. 2018;37(9):1237-1250. doi:10.1038/s41388-017-0018-x

Souche R, Fuks D, Perinel J, Herrero A, Guillon F, Pirlet I, Perniceni T, Cunha A, Gayet B, Fabre J-M Impact of laparoscopy in patients aged over 70 years requiring distal pancreatectomy: a French multicentric comparative study. Surg Endosc. 2018;32(7):3164-3173. doi:10.1007/s00464-018-6033-3

Costanza B, Umelo I, Bellier J, Castronovo V, Turtoi A Stromal Modulators of TGF-? in Cancer. J Clin Med. 2017;6(1). doi:10.3390/jcm6010007

Blomme A, Costanza B, de Tullio P, Thiry M, Van Simaeys G, Boutry S, Doumont G, Di Valentin E, Hirano T, Yokobori T, Gofflot S, Peulen O, Bellahcene A, Sherer F, Le Goff C, Cavalier E, Mouithys-Mickalad A, Jouret F, Cusumano P, Lifrange E, Muller R, Goldman S, Delvenne P, De Pauw E, Nishiyama M, Castronovo V, Turtoi A Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer. Oncogene. Oct 24 2016. doi:10.1038/onc.2016.369


Team

Team Leader  : Andreï Turtoi
 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle
34298 Montpellier cedex 5


 

Tél. 33 (0)4 11 28 31 88
andrei.turtoi@inserm.fr

Partners / Funding

       


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés