Research
Epithelial Growth and Cancer : A. Djiane

activities

We study short-range (stress response & cell competition) and long-range (interorgan exchanges & cachexia) cellular interactions during tumour development.

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MAIN PUBLICATIONS

Rodríguez-Vázquez M, Falconi J, Heron-Milhavet L, Lassus P, Géminard C, Djiane A Fat body glycolysis defects inhibit mTOR and promote distant muscle disorganization through TNF-?/egr and ImpL2 signaling in Drosophila larvae. EMBO Rep. 2024-09-09. doi:10.1038/s44319-024-00241-3

Logeay R, Géminard C, Lassus P, Rodríguez-Vázquez M, Kantar D, Fischer B, Bray S, Colinge J, Djiane A Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila. Development. 2022-01-10. doi:10.1242/dev.200110

Kantar D, Mur E, Mancini M, Slaninova V, Salah Y, Costa L, Forest E, Lassus P, Géminard C, Boissičre-Michot F, Orsetti B, Theillet C, Colinge J, Benistant C, Maraver A, Heron-Milhavet L, Djiane A MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis. Sci Rep. 2021;11(1):5752. doi:10.1038/s41598-021-85056-1

Forest E, Logeay R, Géminard C, Kantar D, Frayssinoux F, Heron-Milhavet L, Djiane A The apical scaffold big bang binds to spectrins and regulates the growth of Drosophila melanogaster wing discs. J. Cell Biol.. 2018;217(3):1047-1062. doi:10.1083/jcb.201705107

Zaessinger S, Zhou Y, Bray S, Tapon N, Djiane A Drosophila MAGI interacts with RASSF8 to regulate E-Cadherin-based adherens junctions in the developing eye. Development. 2015;142. doi:10.1242/dev.116277


Team

Team Leader : Alexandre Djiane
 

Institut de Recherche en
Cancérologie de Montpellier
Campus Val d’Aurelle
34298 Montpellier cedex 5


 

Tél. : 33 (0)4 67 61 24 41
Fax : 33 (0)4 67 61 37 87

alexandre.djiane@inserm.fr

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partners / funding

     


© Institut de Recherche en Cancérologie de Montpellier - 2011 - Tous droits réservés - Mentions légales - Connexion - Conception : ID Alizés