Lahalle A, Lacroix M, De Blasio C, Cissé M, Linares L, Le Cam L The p53 Pathway and Metabolism: The Tree That Hides the Forest. Cancers. 2021;13(1):133. doi:10.3390/cancers13010133
Cissé M, Pyrdziak S, Firmin N, Gayte L, Heuillet M, Bellvert F, Fuentes M, Delpech H, Riscal R, Arena G, Chibon F, Le Gellec S, Maran-Gonzalez A, Chateau M-C, Theillet C, Portais J-C, Le Cam L, Linares L Targeting MDM2-dependent serine metabolism as a therapeutic strategy for liposarcoma. Sci. Transl. Med.. 2020;12(547):eaay2163. doi:10.1126/scitranslmed.aay2163
Quénet F, Pissas M-H, Gil H, Roca L, Carrère S, Sgarbura O, Rouanet P, de Forges H, Khellaf L, Deshayes E, Ychou M, Bibeau F Two-stage hepatectomy for colorectal liver metastases: Pathologic response to preoperative chemotherapy is associated with second-stage completion and longer survival. 2019;165(4):703-711. doi:10.1016/j.surg.2018.10.006
Darlix A, Hirtz C, Thezenas S, Maceski A, Gabelle A, Lopez-Crapez E, Firmin N, Guiu S, Jacot W, Lehmann S The prognostic value of the Tau protein serum level in metastatic breast cancer patients and its correlation with brain metastases. 2019;19(1). doi:10.1186/s12885-019-5287-z
Champagne J, Linares L, Maurel B, Zampieri A, Moreno M, Fuentes I, Dubois E, Severac D, Decorsière A, Bienvenu F TAG-RNAi overcomes off-target effects in cancer models. Oncogene. Sep 26, 2019. doi:10.1038/s41388-019-1020-2
Pons-Tostivint E, Kirova Y, Campone M, Geffrelot J, Mazouni C, Mailliez A, Pasquier D, Madranges N, Firmin N, Crouzet A, Jankowski C, De La Motte Rouge T, Pouget N, de La Lande B, Mouttet-Boizat D, Ferrero J-M, Uwer L, Eymard J-C, Mouret-Reynier M-A, Petit T, Robain M, Filleron T, Cailliot C, Dalenc F Survival Impact of Locoregional Treatment of the Primary Tumor in De Novo Metastatic Breast Cancers in a Large Multicentric Cohort Study: A Propensity Score-Matched Analysis. 2019;26(2):356-365. doi:10.1245/s10434-018-6831-9
Blay J-Y, Honoré C, Stoeckle E, Jafari M, Gouin F, Anract P, Ferron G, Rochwerger A, Ropars M, Carrere S, Marchal F, Sirveaux F, Di Marco A, Le Nail L, Guiramand J, Vaz G, Machiavello J-C, Marco O, Causeret S, Gimbergues P, Fiorenza F, Chaigneau L, Guillemin F, Guilloit J-M, Dujardin F, Spano J-P, Ruzic J-C, Michot A, Soibinet P, Bompas E, Chevreau C, Duffaud F, Rios M, Perrin C, Firmin N, Bertucci F, Le Loarer F, Collard O, Karanian-Philippe M, Brahmi M, Dufresne A, Dupré A, Ducimetière F, Giraud A, Pérol D, Toulmonde M, Ray-Coquard I, Italiano A, Le Cesne A, Penel N, Bonvalot S Surgery in reference centers improves survival of sarcoma patients: a nationwide study. Ann. Oncol.. 06 05, 2019. doi:10.1093/annonc/mdz170
Hodgkinson A, Le Cam L, Trucu D, Radulescu O Spatio-Genetic and phenotypic modelling elucidates resistance and re-sensitisation to treatment in heterogeneous melanoma. Journal of Theoretical Biology. 2019;466. doi:10.1016/j.jtbi.2018.11.037
Tetreau R, Honoré C, Tzanis D, Delhorme J-B, Fau M, Decanter G, Llacer C, Firmin N, Stoeckle E, Ferron G, Cupissol D, Meunier B, Bonvalot S Quelle prise en charge optimale pour un sarcome du cordon spermatique en 2018 ?. 2019;29(1):12-17. doi:10.1016/j.purol.2018.09.010
Arena G, Cissé M, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold J, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Marine J-C, Etienne-Manneville S, Bernex F, Lombès A, Cameron C, Dubouchaud H, Ricchetti M, Linares L, Le Cam L Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53. Mol. Cell. 2018;69(4):594-609.e8. doi:10.1016/j.molcel.2018.01.023
Arena G, Riscal R, Linares L, Le Cam L MDM2 controls gene expression independently of p53 in both normal and cancer cells. Cell Death Differ.. 2018;25(9):1533-1535. doi:10.1038/s41418-018-0156-x
Bertoli S, Picard M, Bérard E, Griessinger E, Larrue C, Mouchel P, Vergez F, Tavitian S, Yon E, Ruiz J, Delabesse E, Luquet I, Linares L, Saland E, Carroll M, Danet-Desnoyers G, Sarry A, Huguet F, Sarry J, Récher C Dexamethasone in hyperleukocytic acute myeloid leukemia. Haematologica. 2018;103(6):988-998. doi:10.3324/haematol.2017.184267
Delhorme J-B, Severac F, Averous G, Glehen O, Passot G, Bakrin N, Marchal F, Pocard M, Lo Dico R, Eveno C, Carrere S, Sgarbura O, Quenet F, Ferron G, Goéré D, Brigand C Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei of appendicular and extra-appendicular origin: Treatment of appendicular and extra-appendicular pseudomyxoma peritonei. 2018;105(6):668-676. doi:10.1002/bjs.10716
Griguolo G, Pouderoux S, Dieci M, Jacot W, Bourgier C, Miglietta F, Firmin N, Viala M, Guarneri V, Darlix A Clinicopathological and Treatment?Associated Prognostic Factors in Patients with Breast Cancer Leptomeningeal Metastases in Relation to Tumor Biology. 2018;23(11):1289-1299. doi:10.1634/theoncologist.2018-0200
Montagner A, Le Cam L, Guillou H ?-catenin oncogenic activation rewires fatty acid catabolism to fuel hepatocellular carcinoma. Gut. Aug 04, 2018. doi:10.1136/gutjnl-2018-316557
Gelmetti V, De Rosa P, Torosantucci L, Marini E, Romagnoli A, Di Rienzo M, Arena G, Vignone D, Fimia G, Valente E PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation. Autophagy. 2017;13. doi:10.1080/15548627.2016.1277309
Farge T, Saland E, de Toni F, Aroua N, Hosseini M, Perry R, Bosc C, Sugita M, Stuani L, Fraisse M, Scotland S, Larrue C, Boutzen H, Feliu V, Nicolau-Travers M, Cassant-Sourdy S, Broin N, David M, Serhan N, Sarry A, Tavitian S, Kaoma T, Vallar L, Iacovoni J, Linares L, Montersino C, Castellano R, Griessinger E, Collette Y, Duchamp O, Barreira Y, Hirsch P, Palama T, Gales L, Delhommeau F, Garmy-Susini B, Portais J, Vergez F, Selak M, Danet-Desnoyers G, Carroll M, Recher C, Sarry J Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism. Cancer discovery. Apr 17 2017. doi:10.1158/2159-8290.CD-16-0441
Bertrand M, Colombo P-E, Mourregot A, Traore D, Carrère S, Quénet F, Rouanet P Standardized single docking, four arms and fully robotic proctectomy for rectal cancer: the key points are the ports and arms placement. 2016;10(2):171-174. doi:10.1007/s11701-015-0551-y
Darlix A, Lamy P-J, Lopez-Crapez E, Braccini A, Firmin N, Romieu G, Jacot W Serum NSE, MMP-9 and HER2 extracellular domain are associated with brain metastases in metastatic breast cancer patients: predictive biomarkers for brain metastases?: NSE, MMP-9 and HER2 Extracellular Domain in Breast Cancer Brain Metastases. 2016;139(10):2299-2311. doi:10.1002/ijc.30290
Darlix A, Lamy P-J, Lopez-Crapez E, Braccini A, Firmin N, Romieu G, Thezenas S, Jacot W Serum HER2 extra-cellular domain, S100ß and CA 15-3 levels are independent prognostic factors in metastatic breast cancer patients. 2016;16(1). doi:10.1186/s12885-016-2448-1
Colombo P-E, Bertrand M, Alline M, Boulay E, Mourregot A, Carrère S, Quénet F, Jarlier M, Rouanet P Robotic Versus Laparoscopic Total Mesorectal Excision (TME) for Sphincter-Saving Surgery: Is There Any Difference in the Transanal TME Rectal Approach?: A Single-Center Series of 120 Consecutive Patients. 2016;23(5):1594-1600. doi:10.1245/s10434-015-5048-4
Llacer-Moscardo C, Bourgier C, Morel A, Fenoglietto P, Firmin N, Azria D Radiothérapie des sarcomes des tissus mous des membres : évolution technique et impact sur le bénéfice clinique. 2016;20(6-7):666-676. doi:10.1016/j.canrad.2016.07.074
Sgarbura O, Samalin E, Mazard T, Forges H, Alline M, Pissas M-H, Portales F, Ychou M Preoperative intraperitoneal oxaliplatin for unresectable peritoneal carcinomatosis of colorectal origin: a pilot study. 2016;1(4). doi:10.1515/pp-2016-0018
Bertrand M, Carrère S, Delmond L, Mehta S, Rouanet P, Canaud L, Alric P, Quénet F Oncovascular compartmental resection for retroperitoneal soft tissue sarcoma with vascular involvement. 2016;64(4):1033-1041. doi:10.1016/j.jvs.2016.04.006
Boutzen H, Saland E, Larrue C, de Toni F, Gales L, Castelli F, Cathebas M, Zaghdoudi S, Stuani L, Kaoma T, Riscal R, Yang G, Hirsch P, David M, De Mas-Mansat V, Delabesse E, Vallar L, Delhommeau F, Jouanin I, Ouerfelli O, Le Cam L, Linares L, Junot C, Portais J, Vergez F, Recher C, Sarry J Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia. The Journal of experimental medicine. 2016;213. doi:10.1084/jem.20150736
Institut de Recherche en Cancérologie de
