LiPiCS Services (Lyon-France)
contact : Eric JULIEN (CNRS/Inserm)
Protein-protein interactions are a key factor to understand a protein function. As we tried to identify molecular mechanisms explaining the pro and anti-tumoral effect of a well known transcription family, we developped a Bimolecular Fluorescence Complementation based asssay to screen in live cell line for whole interactome of a target. Reaching higher robustness than other screening technology, we performed comparative analysis to understand the effect of differents effectors and mutations on target interactome.
LiPiCS Services (Lyon-France)
contact : Eric JULIEN (CNRS/Inserm)
Protein-protein interactions are a key factor to understand a protein function. As we tried to identify molecular mechanisms explaining the pro and anti-tumoral effect of a well known transcription family, we developped a Bimolecular Fluorescence Complementation based asssay to screen in live cell line for whole interactome of a target. Reaching higher robustness than other screening technology, we performed comparative analysis to understand the effect of differents effectors and mutations on target interactome.
INTEGRAGEN, Genopole Campus, Evry (Paris)
contact : Pierre-François ROUX (equipe L. LeCam-INSERM)
INTEGRAGEN, Genopole Campus, Evry (Paris)
contact : Pierre-François ROUX (equipe L. LeCam-INSERM)
Institut Pasteur, Department of Developmental and Stem Cell Biology
contact : Alexandre Djiane (IRCM)
Institut Pasteur, Department of Developmental and Stem Cell Biology
contact : Alexandre Djiane (IRCM)
Institut Pasteur, Department of Developmental and Stem Cell Biology
contact : Alexandre Djiane (IRCM)
Institut Pasteur, Department of Developmental and Stem Cell Biology
contact : Alexandre Djiane (IRCM)
INSERM U1280
Institute for Integrative Biology of the Cell (I2BC)
University Paris-Saclay-CEA-CNRS; Gif/Yvette
contact : Alexandre Djiane (Inserm-IRCM)
INSERM U1280
Institute for Integrative Biology of the Cell (I2BC)
University Paris-Saclay-CEA-CNRS; Gif/Yvette
contact : Alexandre Djiane (Inserm-IRCM)