Radiobiology for Targeted and Personalized Radiotherapy : Jean-Pierre POUGET & David AZRIA

Liste des Publications

Deshayes E, Fersing C, Hébert K, Kotzki P, Santoro L Whole body planar and 3D quantitative imaging after 177Lu-DOTATATE on CZT SPECT/CT device with MEHRS collimator. First report. Hell J Nucl Med. 2021;24(2):165-166. doi:10.1967/s002449912361

Idrissou M, Pichard A, Tee B, Kibedi T, Poty S, Pouget J-P Targeted Radionuclide Therapy Using Auger Electron Emitters: The Quest for the Right Vector and the Right Radionuclide. Pharmaceutics. 2021;13(7):980. doi:10.3390/pharmaceutics13070980

Larroque M, Mounicou S, Sgarbura O, Arnaudguilhem C, Rebel L, Leaha C, Faye P-A, Enjalbal C, Quénet F, Bouyssiere B Study of oxaliplatin penetration into ovaries of patients treated with hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal metastases of colorectal and appendiceal origin using mass spectrometry imaging. Pleura Peritoneum. 2021;6(2):67-74. doi:10.1515/pp-2020-0149

Gear J Scientific Developments in Imaging and Dosimetry for Molecular Radiotherapy. Clin Oncol (R Coll Radiol). 2021;33(2):117-124. doi:10.1016/j.clon.2020.11.005

Pouget J-P, Constanzo J Revisiting the Radiobiology of Targeted Alpha Therapy. Front Med (Lausanne). 2021;8. doi:10.3389/fmed.2021.692436

Karam J, Constanzo J, Pichard A, Gros L, Chopineau J, Morille M, Pouget J-P Rapid communication: insights into the role of extracellular vesicles during Auger radioimmunotherapy. Int J Radiat Biol. 2021-07-26. doi:10.1080/09553002.2021.1955999

Constanzo J, Faget J, Ursino C, Badie C, Pouget J-P Radiation-Induced Immunity and Toxicities: The Versatility of the cGAS-STING Pathway. Front Immunol. 2021;12. doi:10.3389/fimmu.2021.680503

Cornelissen B, Terry S, Nonnekens J, Pouget J-P First Symposium of the European Working Group on the Radiobiology of Molecular Radiotherapy. J Nucl Med. 2021;62(7):14N-15N.

Santoro L, Pitalot L, Trauchessec D, Mora-Ramirez E, Kotzki P, Deshayes E Clinical implementation of PLANET® Dose for dosimetric assessment after [177Lu]Lu-DOTA-TATE: comparison with Dosimetry Toolkit® and OLINDA/EXM® V1.0. EJNMMI Res. 2021;11(1):1. doi:10.1186/s13550-020-00737-8

Pichard A, Marcatili S, Karam J, Constanzo J, Ladjohounlou R, Courteau A, Jarlier M, Bonnefoy N, Patzke S, Stenberg V, Coopman P, Cartron G, Navarro-Teulon I, Repetto-Llamazares A, Heyerdahl H, Dahle J, Bardiès M, Pouget J-P The therapeutic effectiveness of 177Lu-lilotomab in B-cell non-Hodgkin lymphoma involves modulation of G2/M cell cycle arrest. Leukemia. 2020;34(5):1315-1328. doi:10.1038/s41375-019-0677-4

Re?nik L-M, Cantelli C, Fersing C, Gongora C, Pouget J-P, Lisowski V Synthesis and in vitro antitumour activity of carboplatin analogues containing functional handles compatible for conjugation to drug delivery systems. Bioorg Med Chem Lett. 2020;30(22):127527. doi:10.1016/j.bmcl.2020.127527

Bordes J, Incerti S, Mora-Ramirez E, Tranel J, Rossi C, Bezombes C, Bordenave J, Bardiès M, Brown R, Bordage M-C Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy. Med Phys. 2020;47(10):5222-5234. doi:10.1002/mp.14370

Bourillon L, Demontoy S, Lenglet A, Zampieri A, Fraisse J, Jarlier M, Boissière-Michot F, Perrochia H, Rathat G, Garambois V, Bonnefoy N, Michaud H-A, Chardès T, Tosi D, Pèlegrin A, Azria D, Larbouret C, Bourgier C Higher Anti-Tumor Efficacy of the Dual HER3-EGFR Antibody MEHD7945a Combined with Ionizing Irradiation in Cervical Cancer Cells. Int J Radiat Oncol Biol Phys. 2020;106(5):1039-1051. doi:10.1016/j.ijrobp.2019.12.020

Constanzo J, Midavaine É, Fouquet J, Lepage M, Descoteaux M, Kirby K, Tremblay L, Masson-Côté L, Geha S, Longpré J-M, Paquette B, Sarret P Brain irradiation leads to persistent neuroinflammation and long-term neurocognitive dysfunction in a region-specific manner. Prog Neuropsychopharmacol Biol Psychiatry. 2020;102. doi:10.1016/j.pnpbp.2020.109954

Quénet F, Pissas M-H, Gil H, Roca L, Carrère S, Sgarbura O, Rouanet P, de Forges H, Khellaf L, Deshayes E, Ychou M, Bibeau F Two-stage hepatectomy for colorectal liver metastases: Pathologic response to preoperative chemotherapy is associated with second-stage completion and longer survival. Surgery. 2019;165(4):703-711. doi:10.1016/j.surg.2018.10.006

Maïmoun L, Mariano-Goulart D, Jaussent A, Lefebvre P, Picot M-C, Mahadea K, Boudousq V, Fouillade C, Nocca D, Fayçal B The effect of excessive fat tissue on the measure of bone mineral density by dual-X ray absorptiometry: the impact of substantial weight loss following sleeve gastrectomy. Clin Physiol Funct Imaging. May 15, 2019. doi:10.1111/cpf.12584

Rondon A, Schmitt S, Briat A, Ty N, Maigne L, Quintana M, Membreno R, Zeglis B, Navarro-Teulon I, Pouget J-P, Chezal J-M, Miot-Noirault E, Moreau E, Degoul F Pretargeted radioimmunotherapy and SPECT imaging of peritoneal carcinomatosis using bioorthogonal click chemistry: probe selection and first proof-of-concept. Theranostics. 2019;9(22):6706-6718. doi:10.7150/thno.35461

Panaro F, Giannone F, Sgarbura O, Cusumano C, Deshayes E, Navarro F, Guiu B Perioperative impact of liver venous deprivation compared with portal venous embolization in patients undergoing right hepatectomy: preliminary results from the pioneer center. Hepatobiliary Surg Nutr. 2019;8(4):329-337. doi:10.21037/hbsn.2019.07.06

Ashraf Y, Mansouri H, Laurent-Matha V, Alcaraz L, Roger P, Guiu S, Derocq D, Robin G, Michaud H-A, Jarlier M, Pugnière M, Robert B, Puel A, Martin L, Landomiel F, Bourquard T, Achour O, Fruitier-Arnaudin I, Pichard A, Deshayes E, Turtoi A, Poupon A, Boissière-Michot F, Pirot N, Bernex F, Jacot W, du Manoir S, Theillet C, Pouget J-P, Navarro-Teulon I, Bonnefoy N, Pèlegrin A, Chardès T, Martineau P, Liaudet-Coopman E Immunotherapy of triple-negative breast cancer with cathepsin D-targeting antibodies. J Immunother Cancer. 2019;7(1):29. doi:10.1186/s40425-019-0498-z

Ladjohounlou R, Lozza C, Pichard A, Constanzo J, Karam J, Le Fur P, Deshayes E, Boudousq V, Paillas S, Busson M, Le Blay M, Jarlier M, Marcatili S, Bardiès M, Bruchertseifer F, Morgenstern A, Torgue J, Navarro-Teulon I, Pouget J-P Drugs That Modify Cholesterol Metabolism Alter the p38/JNK-Mediated Targeted and Nontargeted Response to Alpha and Auger Radioimmunotherapy. Clin Cancer Res. 2019;25(15):4775-4790. doi:10.1158/1078-0432.CCR-18-3295

Terry S, Nonnekens J, Aerts A, Baatout S, de Jong M, Cornelissen B, Pouget J-P Call to arms: need for radiobiology in molecular radionuclide therapy. Eur J Nucl Med Mol Imaging. 2019;46(8):1588-1590. doi:10.1007/s00259-019-04334-3

Pouget J-P, Georgakilas A, Ravanat J-L Targeted and Off-Target (Bystander and Abscopal) Effects of Radiation Therapy: Redox Mechanisms and Risk/Benefit Analysis. Antioxid. Redox Signal.. 2018;29(15):1447-1487. doi:10.1089/ars.2017.7267

Deshayes E, Ladjohounlou R, Le Fur P, Pichard A, Lozza C, Boudousq V, Sevestre S, Jarlier M, Kashani R, Koch J, Sosabowski J, Foster J, Chouin N, Bruchertseifer F, Morgenstern A, Kotzki P-O, Navarro-Teulon I, Pouget J-P Radiolabeled Antibodies Against Müllerian-Inhibiting Substance Receptor, Type II: New Tools for a Theranostic Approach in Ovarian Cancer. J. Nucl. Med.. 2018;59(8):1234-1242. doi:10.2967/jnumed.118.208611

Santoro L, Mora-Ramirez E, Trauchessec D, Chouaf S, Eustache P, Pouget J-P, Kotzki P-O, Bardiès M, Deshayes E Implementation of patient dosimetry in the clinical practice after targeted radiotherapy using [177Lu-[DOTA0, Tyr3]-octreotate. EJNMMI Res. 2018;8(1):103. doi:10.1186/s13550-018-0459-4

Renard D, Collombier L, Demattei C, Wacongne A, Charif M, Ayrignac X, Azakri S, Gaillard N, Boudousq V, Lehmann S, Menjot de Champfleur N, Thouvenot E Cerebrospinal Fluid, MRI, and Florbetaben-PET in Cerebral Amyloid Angiopathy-Related Inflammation. J. Alzheimers Dis.. 2018;61(3):1107-1117. doi:10.3233/JAD-170843

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